A paper describing the nanoneedle was published in the Proceedings of the National Academy of Sciences. Ronald W. Davis, Ph.D. is the senior author. Rahim Esfandyarpour, Ph.D. is the lead author.
The nanoneedle is a test that measures changes in immune cells with their blood plasma as a result of salt stress. Inside the nanoneedle, the immune cells interfere with a small electric current. The change in electrical activity is directly correlated with the health of the sample.
With blood samples from 40 people — 20 with ME / CFS and 20 without — the test yielded precise results, accurately flagging all patients and none of the healthy individuals.